Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22837744 | 1.00 | KDM4E (0.70) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL22861693 | 1.00 | KDM4E (0.70) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL21452622 | 0.98 | KDM4E (0.65) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL16750033 | 0.93 | KDM4E (0.58) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL25477591 | 0.90 | PAOX (0.60) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL22802988 | 0.88 | KDM4E (0.54) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL21106556 | 0.88 | KDM4E (0.59) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL23806728 | 0.84 | KDM4E (0.48) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL2390501 | 0.84 | KDM4E (0.50) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL1900654 | 0.83 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020156513-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | 同宜医药（苏州）有限公司 | 2020-08-06 | — | — | WO | disclosed |
| WO-2020160192-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |