Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 6/20 | 0.56 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22300110 | 0.88 | KIT (0.55) | KITENPP1MAPK1MEN1KMT2A | |
| SCHEMBL30288430 | 0.86 | KIT (0.53) | KITENPP1MAPK1MEN1KMT2A | |
| SCHEMBL24008971 | 0.86 | KIT (0.53) | KITENPP1MAPK1MEN1KMT2A | |
| SCHEMBL22164657 | 0.85 | KIT (0.57) | KITENPP1MAPK1MEN1KMT2A | |
| SCHEMBL22164766 | 0.85 | KIT (0.57) | KITENPP1MAPK1MEN1KMT2A | |
| SCHEMBL27112175 | 0.85 | KIT (0.52) | KITENPP1MAPK1MEN1KMT2A | |
| SCHEMBL31400270 | 0.83 | KIT (0.50) | KITENPP1MAPK1MEN1KMT2A | |
| SCHEMBL28647820 | 0.83 | KIT (0.50) | KITENPP1MAPK1MEN1KMT2A | |
| SCHEMBL20813395 | 0.83 | KIT (0.50) | KITENPP1MAPK1MEN1KMT2A | |
| SCHEMBL24008967 | 0.82 | KIT (0.53) | KITENPP1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160333-A1 | ENPP1 INHIBITORS AND METHODS OF MODULATING IMMUNE RESPONSE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-08-06 | — | — | WO | disclosed |