Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 6/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 11/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288664 | 0.89 | PDE3B (0.57) | PDE3BPDE3AMAOB | |
| SCHEMBL22289023 | 0.81 | PDE3B (0.41) | PDE3BPDE3ANR3C2NR3C1PGR | |
| SCHEMBL20703432 | 0.81 | PDE3B (0.45) | PDE3BPDE3A | |
| SCHEMBL22308358 | 0.80 | PDE3B (0.44) | PDE3BPDE3ANR3C2NR3C1PGR | |
| SCHEMBL22288643 | 0.77 | PDE3B (0.42) | PDE3BPDE3AMAOB | |
| SCHEMBL22304763 | 0.75 | MAOB (0.56) | PDE3BPDE3AMAOB | |
| SCHEMBL22288965 | 0.75 | MAOB (0.56) | PDE3BPDE3AMAOB | |
| SCHEMBL22288706 | 0.74 | MAOB (0.50) | PDE3BPDE3AMAOB | |
| SCHEMBL22304786 | 0.74 | PDE3B (0.65) | PDE3BPDE3AMAOB | |
| SCHEMBL22288970 | 0.72 | PDE3B (0.63) | PDE3BPDE3AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157201-A1 | OXADIAZINONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |