Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 18/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 18/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22304747 | 0.89 | PDE3B (0.56) | PDE3BPDE3AMAOB | |
| SCHEMBL22304648 | 0.88 | PDE3B (0.64) | PDE3BPDE3AMAOB | |
| SCHEMBL22304508 | 0.86 | PDE3B (0.65) | PDE3BPDE3AMAOB | |
| SCHEMBL22288400 | 0.86 | PDE3B (0.49) | PDE3BPDE3AMAOB | |
| SCHEMBL22304848 | 0.85 | PDE3B (0.58) | PDE3BPDE3AMAOB | |
| SCHEMBL22304647 | 0.85 | MAOB (0.57) | PDE3BPDE3AMAOB | |
| SCHEMBL22288412 | 0.83 | PDE3B (0.67) | PDE3BPDE3A | |
| SCHEMBL22304672 | 0.82 | PDE3B (0.66) | PDE3BPDE3AMAOB | |
| SCHEMBL22288706 | 0.80 | MAOB (0.50) | PDE3BPDE3AMAOB | |
| SCHEMBL22304511 | 0.78 | PDE3B (0.61) | PDE3BPDE3AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157201-A1 | OXADIAZINONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |