Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 12/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 12/20 | 0.42 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288394 | 0.89 | PDE3B (0.49) | CNR2PDE3BPDE3AMAOB | |
| SCHEMBL22288612 | 0.86 | PDE3B (0.41) | PDE3BPDE3AMAOBNOTUM | |
| SCHEMBL22304683 | 0.85 | PDE3B (0.38) | CNR2PDE3BPDE3AMAOB | |
| SCHEMBL22288640 | 0.85 | PDE3B (0.48) | PDE3BPDE3AMAOB | |
| SCHEMBL22304784 | 0.85 | PDE3B (0.52) | CNR2PDE3BPDE3AMAOB | |
| SCHEMBL22304677 | 0.83 | PDE3B (0.40) | PDE3BPDE3AMAOB | |
| SCHEMBL22304783 | 0.81 | PDE3B (0.61) | PDE3BPDE3ANOTUM | |
| SCHEMBL22288634 | 0.81 | PDE3B (0.61) | PDE3BPDE3ANOTUM | |
| SCHEMBL22288643 | 0.79 | PDE3B (0.42) | PDE3BPDE3AMAOB | |
| SCHEMBL22304510 | 0.79 | MAOB (0.46) | PDE3BPDE3AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157201-A1 | OXADIAZINONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |