⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22305304 | 0.80 | — | — | |
| SCHEMBL22305023 | 0.75 | — | — | |
| SCHEMBL16786174 | 0.74 | TSHR (0.38) | — | |
| SCHEMBL13525850 | 0.69 | — | — | |
| SCHEMBL24361245 | 0.68 | TSHR (0.32) | — | |
| SCHEMBL19501028 | 0.67 | TSHR (0.31) | — | |
| SCHEMBL16789734 | 0.67 | TSHR (0.31) | — | |
| SCHEMBL23776866 | 0.67 | TSHR (0.36) | — | |
| SCHEMBL14204444 | 0.67 | TSHR (0.31) | — | |
| SCHEMBL27256739 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160192-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |