SCHEMBL22305484

SCHEMBL22305484

C1=NCCOCCOCC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25294952 0.97
SCHEMBL21778836 0.78 TTR (0.33) TTR
SCHEMBL29508642 0.74
SCHEMBL519611 0.71
SCHEMBL1014317 0.71
SCHEMBL29508605 0.67
SCHEMBL380648 0.67
Hydrochloric Acid SCHEMBL8763529 0.63
SCHEMBL8130613 0.61 TTR (0.50) TTRALDH1A1
SCHEMBL7530365 0.61 TTR (0.50) TTRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020160180-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2020-08-06 WO disclosed