Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916877 | 0.99 | KMT2A (0.41) | KMT2ATDP1TAAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL637123 | 0.89 | KMT2A (0.41) | KMT2ATDP1TAAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2231234 | 0.89 | KMT2A (0.41) | KMT2ATDP1TAAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2231584 | 0.88 | TAAR1 (0.41) | KMT2ATDP1TAAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL637975 | 0.88 | KMT2A (0.40) | KMT2ATDP1TAAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL915583 | 0.88 | KMT2A (0.40) | KMT2ATDP1TAAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL640972 | 0.87 | TAAR1 (0.41) | KMT2ATDP1TAAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL636260 | 0.87 | ELANE (0.40) | KMT2ATDP1TAAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL916906 | 0.85 | TAAR1 (0.43) | KMT2ATDP1TAAR1ALDH1A1LMNA | |
| SCHEMBL2230122 | 0.85 | TAAR1 (0.42) | KMT2ATDP1TAAR1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2354120-A1 | Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof | XenoPort, Inc. (US) | 2011-08-10 | — | — | EP | disclosed |
| WO-2008157408-A2 | USE OF PRODRUGS OF GABA ANALOGS, ANTISPASTICITY AGENTS, AND PRODRUGS OF GABA B RECEPTOR AGONISTS FOR TREATING SPASTICITY | XENOPORT, INC. (US) | 2008-12-24 | — | — | WO | disclosed |