Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.35 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.34 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22907204 | 0.82 | CRBN (0.39) | CRBNDDB1ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL22907126 | 0.80 | CRBN (0.41) | CRBNDDB1ALDH1A1IKZF2IKZF1 | |
| SCHEMBL22907124 | 0.78 | CRBN (0.59) | CRBNDDB1ALDH1A1IKZF2IKZF1 | |
| SCHEMBL22907014 | 0.78 | CRBN (0.59) | CRBNDDB1ALDH1A1IKZF2IKZF1 | |
| SCHEMBL24379430 | 0.78 | CRBN (0.66) | CRBNDDB1ALDH1A1IKZF2IKZF1 | |
| SCHEMBL22301791 | 0.78 | CRBN (0.66) | CRBNDDB1ALDH1A1IKZF2IKZF1 | |
| SCHEMBL25802711 | 0.78 | CRBN (0.40) | CRBNDDB1ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL24379441 | 0.78 | CRBN (0.66) | CRBNDDB1ALDH1A1IKZF2IKZF1 | |
| SCHEMBL22306101 | 0.78 | CRBN (0.65) | CRBNDDB1ALDH1A1IKZF2IKZF1 | |
| SCHEMBL22907414 | 0.77 | CRBN (0.54) | CRBNDDB1ALDH1A1IKZF1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160192-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |