SCHEMBL22306512

SCHEMBL22306512

OSc1ccc2c(c1F)OCC2

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.38
DAO P14920 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25981460 0.76 PARP1 (0.41) PARP1DAO
SCHEMBL28357979 0.75 PARP1 (0.39) PARP1DAO
SCHEMBL23729377 0.72 PARP1 (0.37) PARP1DAO
SCHEMBL31630067 0.72 PARP1 (0.37) PARP1DAO
SCHEMBL22290551 0.71 PARP1 (0.38) PARP1DAO
SCHEMBL23987367 0.70
SCHEMBL26700329 0.68 PARP1 (0.34) PARP1DAO
SCHEMBL31719478 0.66 PARP1 (0.43) PARP1DAO
SCHEMBL31040186 0.64 PARP1 (0.38) PARP1DAO
SCHEMBL28892505 0.64 PARP1 (0.38) PARP1DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020160180-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2020-08-06 WO disclosed