Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.65 |
| ▸ | MAP1LC3B | Q9GZQ8 | 4/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.56 |
| ▸ | IKZF3 | Q9UKT9 | 5/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.55 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.55 |
| ▸ | BRD4 | O60885 | 2/20 | 0.55 |
| ▸ | TNF | P01375 | 2/20 | 0.55 |
| ▸ | IL1B | P01584 | 1/20 | 0.55 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21303964 | 0.93 | STAT3 (0.65) | STAT3MAP1LC3BCRBNIKZF3DDB1 | |
| SCHEMBL21303972 | 0.93 | STAT3 (0.67) | STAT3MAP1LC3BCRBNIKZF3DDB1 | |
| SCHEMBL30189339 | 0.93 | STAT3 (0.65) | STAT3MAP1LC3BCRBNIKZF3DDB1 | |
| SCHEMBL30189386 | 0.93 | STAT3 (0.65) | STAT3MAP1LC3BCRBNIKZF3DDB1 | |
| SCHEMBL17536588 | 0.92 | STAT3 (0.66) | STAT3MAP1LC3BCRBNIKZF3DDB1 | |
| SCHEMBL25431129 | 0.91 | STAT3 (0.67) | STAT3MAP1LC3BCRBNIKZF3DDB1 | |
| SCHEMBL19451277 | 0.91 | STAT3 (0.67) | STAT3MAP1LC3BCRBNIKZF3DDB1 | |
| SCHEMBL20913625 | 0.91 | STAT3 (0.65) | STAT3MAP1LC3BCRBNIKZF3DDB1 | |
| SCHEMBL25226137 | 0.91 | STAT3 (0.67) | STAT3MAP1LC3BCRBNIKZF3DDB1 | |
| SCHEMBL19451341 | 0.91 | STAT3 (0.65) | STAT3MAP1LC3BCRBNIKZF3DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160196-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |