SCHEMBL22307244

SCHEMBL22307244

N#Cc1cc(NC(=O)c2c(Cl)c(C(=O)C(=O)O)n3c2CCC3)ccc1F

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC10A1 Q14973 19/20 0.56
GRM4 Q14833 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382190 1.00 SLC10A1 (0.56) SLC10A1GRM4
SCHEMBL20253012 0.93 SLC10A1 (0.58) SLC10A1
SCHEMBL22308120 0.89 SLC10A1 (0.65) SLC10A1
SCHEMBL21296668 0.88 SLC10A1 (0.52) SLC10A1
SCHEMBL22308107 0.87 SLC10A1 (0.55) SLC10A1
SCHEMBL21810366 0.85 SLC10A1 (0.51) SLC10A1
SCHEMBL22307720 0.85 SLC10A1 (0.65) SLC10A1
SCHEMBL22307700 0.85 SLC10A1 (0.65) SLC10A1
SCHEMBL22308104 0.85 SLC10A1 (0.65) SLC10A1
SCHEMBL30382027 0.85 SLC10A1 (0.65) SLC10A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113365999-B Capsid protein assembly inhibitors containing pyrroloheterocycles 正大天晴药业集团股份有限公司 2023-04-14 CN disclosed
CN-113365999-A Capsid protein assembly inhibitors containing pyrroloheterocycles 正大天晴药业集团股份有限公司 2021-09-07 CN disclosed
WO-2020156494-A1 CAPSID PROTEIN ASSEMBLY INHIBITOR CONTAINING PYRROLO HETEROCYCLE 正大天晴药业集团股份有限公司 2020-08-06 WO disclosed