Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 15/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 15/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22307790 | 0.89 | PDE3B (0.61) | PDE3BPDE3ANOTUMS1PR1 | |
| SCHEMBL22309157 | 0.89 | PDE3B (0.59) | PDE3BPDE3ANOTUM | |
| SCHEMBL22307819 | 0.88 | PDE3B (0.60) | PDE3BPDE3ANOTUM | |
| SCHEMBL22307815 | 0.85 | PDE3B (0.57) | PDE3BPDE3ANOTUM | |
| SCHEMBL22309167 | 0.84 | PDE3B (0.47) | PDE3BPDE3ANOTUM | |
| SCHEMBL22308889 | 0.84 | PDE3B (0.63) | PDE3BPDE3ANOTUM | |
| SCHEMBL22308339 | 0.84 | PDE3B (0.48) | PDE3BPDE3ANOTUM | |
| SCHEMBL22288590 | 0.82 | PDE3B (0.64) | PDE3BPDE3ANOTUM | |
| SCHEMBL22308353 | 0.82 | PDE3B (0.61) | PDE3BPDE3ANOTUM | |
| SCHEMBL22307801 | 0.82 | PDE3B (0.53) | PDE3BPDE3ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157189-A1 | 1,2,4-TRIAZIN-6(1H)-ONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |