⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22309661 | 0.84 | — | — | |
| SCHEMBL12409012 | 0.76 | — | — | |
| SCHEMBL22309845 | 0.65 | — | — | |
| SCHEMBL592371 | 0.65 | GRIN2D (0.33) | — | |
| SCHEMBL12256561 | 0.65 | — | — | |
| SCHEMBL227443 | 0.65 | — | — | |
| SCHEMBL22784173 | 0.65 | — | — | |
| SCHEMBL22776225 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL16210279 | 0.63 | GRIN2D (0.32) | — | |
| SCHEMBL23980179 | 0.62 | CHRNA7 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3919492-A1 | PYRIMIDINYL GROUP-CONTAINING TRICYCLIC COMPOUND SERVING AS C-MET INHIBITOR | Medshine Discovery Inc. (CN) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020156453-A1 | PYRIMIDINYL GROUP-CONTAINING TRICYCLIC COMPOUND SERVING AS C-MET INHIBITOR | 南京明德新药研发有限公司 | 2020-08-06 | — | — | WO | disclosed |