Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 20/20 | 1.00 |
| ▸ | CDK2 | P24941 | 20/20 | 1.00 |
| ▸ | GSK3B | P49841 | 17/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22311821 | 1.00 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL22312348 | 0.93 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL22312409 | 0.92 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL31090787 | 0.91 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL22312724 | 0.91 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL22312740 | 0.91 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL22312484 | 0.91 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL22311815 | 0.91 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL22311441 | 0.91 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL22312725 | 0.89 | CCNE1 (0.88) | CCNE1CDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157652-A2 | CDK2 INHIBITORS | PFIZER INC. (US) | 2020-08-06 | — | — | WO | disclosed |