Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 20/20 | 0.70 |
| ▸ | CDK2 | P24941 | 20/20 | 0.70 |
| ▸ | GSK3B | P49841 | 13/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22311437 | 0.86 | CCNE1 (0.70) | CCNE1CDK2GSK3B | |
| SCHEMBL25334234 | 0.85 | CCNE1 (0.70) | CCNE1CDK2GSK3B | |
| SCHEMBL22312828 | 0.84 | CCNE1 (0.84) | CCNE1CDK2GSK3B | |
| SCHEMBL22286743 | 0.83 | CCNE1 (0.61) | CCNE1CDK2GSK3B | |
| SCHEMBL22287180 | 0.82 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL22287177 | 0.82 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL25334224 | 0.82 | CCNE1 (0.67) | CCNE1CDK2GSK3B | |
| SCHEMBL25335308 | 0.82 | CCNE1 (0.64) | CCNE1CDK2GSK3B | |
| SCHEMBL25334611 | 0.82 | CCNE1 (0.66) | CCNE1CDK2GSK3B | |
| SCHEMBL22312782 | 0.82 | CCNE1 (1.00) | CCNE1CDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157652-A2 | CDK2 INHIBITORS | PFIZER INC. (US) | 2020-08-06 | — | — | WO | disclosed |