Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.55 |
| ▸ | JAK1 | P23458 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22313977 | 0.87 | TYK2 (0.59) | TYK2JAK1JAK2 | |
| SCHEMBL22288328 | 0.85 | TYK2 (0.75) | TYK2JAK1JAK2 | |
| SCHEMBL30065955 | 0.85 | TYK2 (0.75) | TYK2JAK1JAK2 | |
| SCHEMBL30065951 | 0.80 | TYK2 (0.76) | TYK2JAK1CYP2C19JAK2 | |
| SCHEMBL30465841 | 0.79 | TYK2 (0.52) | TYK2JAK1CYP2C19JAK2 | |
| SCHEMBL25670653 | 0.79 | TYK2 (0.52) | TYK2JAK1CYP2C19JAK2 | |
| SCHEMBL17195011 | 0.79 | TYK2 (0.80) | TYK2JAK1JAK2 | |
| SCHEMBL28665049 | 0.77 | TYK2 (0.66) | TYK2JAK1JAK2 | |
| SCHEMBL28665008 | 0.75 | JAK2 (0.74) | TYK2JAK1JAK2 | |
| SCHEMBL31369049 | 0.75 | JAK2 (0.74) | TYK2JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020156311-A1 | PYRIDAZINE DERIVATIVE INHIBITOR, AND PREPARATION METHOD AND APPLICATION THEREOF | 江苏豪森药业集团有限公司 | 2020-08-06 | — | — | WO | disclosed |