Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 20/20 | 1.00 |
| ▸ | PDE3A | Q14432 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22314164 | 0.95 | PDE3B (0.90) | PDE3BPDE3A | |
| SCHEMBL22314300 | 0.91 | PDE3B (1.00) | PDE3BPDE3A | |
| SCHEMBL22314315 | 0.91 | PDE3B (0.83) | PDE3BPDE3A | |
| SCHEMBL22314313 | 0.91 | PDE3B (1.00) | PDE3BPDE3A | |
| SCHEMBL22313744 | 0.89 | PDE3B (0.84) | PDE3BPDE3A | |
| SCHEMBL30882638 | 0.89 | PDE3B (0.80) | PDE3BPDE3A | |
| SCHEMBL22313726 | 0.87 | PDE3B (0.80) | PDE3BPDE3A | |
| SCHEMBL22314247 | 0.85 | PDE3B (1.00) | PDE3BPDE3A | |
| SCHEMBL22288437 | 0.83 | PDE3B (0.71) | PDE3BPDE3A | |
| SCHEMBL28619784 | 0.83 | PDE3B (0.70) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157188-A1 | DIHYDROOXADIAZINONES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |