Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.89 |
| ▸ | FGFR3 | P22607 | 13/20 | 0.89 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rogaratinib SCHEMBL29358162 | 0.94 | FGFR1 (1.00) | FGFR1FGFR3FGFR4 | |
| Rogaratinib SCHEMBL15023004 | 0.94 | FGFR1 (1.00) | FGFR1FGFR3FGFR4 | |
| Rogaratinib SCHEMBL22288911 | 0.93 | FGFR1 (0.99) | FGFR1FGFR3FGFR4 | |
| Rogaratinib SCHEMBL15023316 | 0.93 | FGFR1 (0.99) | FGFR1FGFR3FGFR4 | |
| Rogaratinib SCHEMBL29542499 | 0.93 | FGFR1 (0.97) | FGFR1FGFR3FGFR4 | |
| SCHEMBL15023375 | 0.89 | FGFR1 (1.00) | FGFR1FGFR3FGFR4 | |
| SCHEMBL15023167 | 0.89 | FGFR1 (1.00) | FGFR1FGFR3FGFR4 | |
| SCHEMBL15023048 | 0.88 | FGFR1 (1.00) | FGFR1FGFR3FGFR4 | |
| Hydrochloric Acid SCHEMBL15023352 | 0.88 | FGFR1 (0.99) | FGFR1FGFR3FGFR4 | |
| SCHEMBL15023243 | 0.88 | FGFR1 (1.00) | FGFR1FGFR3FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020156982-A1 | THE MONOHYDRATE OF ROGARATINIB HYDROCHLORIDE AND SOLID STATES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |