⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231537 | 0.81 | — | — | |
| SCHEMBL7883103 | 0.76 | — | — | |
| SCHEMBL10907193 | 0.68 | — | — | |
| SCHEMBL228006 | 0.62 | — | — | |
| SCHEMBL635661 | 0.62 | — | — | |
| SCHEMBL1345915 | 0.61 | TSHR (0.44) | — | |
| SCHEMBL30518832 | 0.57 | — | — | |
| SCHEMBL228008 | 0.57 | — | — | |
| SCHEMBL166709 | 0.55 | — | — | |
| SCHEMBL9777940 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185609-B1 | GAS-PHASE POLYMERIZATION PROCESS | GRACE W R & CO (US) | 2021-01-27 | — | — | EP | disclosed |
| EP-2373698-B2 | ANTIFOULANT FOR IMPACT COPOLYMERS AND METHOD | W R GRACE & CO - CONN (US) | 2017-03-08 | — | — | EP | disclosed |
| US-8604118-B2 | Antifoulant for impact copolymers and method | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-10 | — | — | US | disclosed |
| EP-2373698-B1 | ANTIFOULANT FOR IMPACT COPOLYMERS AND METHOD | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-12-12 | — | — | EP | disclosed |
| US-8324327-B2 | Gas-phase polymerization process | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-12-04 | — | — | US | disclosed |
| EP-2373698-A1 | ANTIFOULANT FOR IMPACT COPOLYMERS AND METHOD | Dow Global Technologies LLC (US) | 2011-10-12 | — | — | EP | disclosed |
| US-20110172377-A1 | Gas-Phase Polymerization Process | W. R. GRACE & CO.-CONN. | 2011-07-14 | — | — | US | disclosed |
| WO-2010075349-A1 | ANTIFOULANT FOR IMPACT COPOLYMERS AND METHOD | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| US-20100167058-A1 | Antifoulant for Impact Copolymers and Method | W. R. GRACE & CO.-CONN. | 2010-07-01 | — | — | US | disclosed |
| EP-2185609-A2 | GAS-PHASE POLYMERIZATION PROCESS | Dow Global Technologies Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009029486-A2 | GAS-PHASE POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-03-05 | — | — | WO | disclosed |