SCHEMBL2231622

SCHEMBL2231622

NCC(=O)N[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1ccc(=O)[nH]c1=O

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.65
SLC28A2 O43868 1/20 0.65
SLC29A1 Q99808 1/20 0.65
SLC28A3 Q9HAS3 1/20 0.65
P2RY6 Q15077 7/20 0.55
P2RY2 P41231 7/20 0.54
P2RY4 P51582 4/20 0.54
P2RY14 Q15391 5/20 0.48
OGT O15294 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6144408 0.92 SLC28A1 (0.63) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL25435066 0.88 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL4540923 0.88 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL14565249 0.87 SLC28A1 (0.68) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL6141738 0.84 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL6141730 0.84 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL3491267 0.84 SLC28A1 (0.64) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL3491264 0.84 SLC28A1 (0.64) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL3491259 0.84 SLC28A1 (0.64) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL25433501 0.84 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8758995-B2 Solid phase sequencing of biopolymers SEQUENOM, INC. (US) 2014-06-24 US disclosed
US-20110172111-A1 SOLID PHASE SEQUENCING OF BIOPOLYMERS SEQUENOM, INC. (US) 2011-07-14 US disclosed
US-7803529-B1 Solid phase sequencing of biopolymers SEQUENOM, INC. (US) 2010-09-28 US disclosed
US-20060063193-A1 Solid phase sequencing of double-stranded nucleic acids TRUSTEES OF BOSTON UNIVERSITY, THE 2006-03-23 US disclosed
US-6991903-B2 Solid phase sequencing of double-stranded nucleic acids SEQUENOM, INC. (US) 2006-01-31 US disclosed
EP-0679196-B1 DNA SEQUENCING BY MASS SPECTROMETRY SEQUENOM INC (US) 2004-05-26 EP disclosed
US-20030096258-A1 Sequencing target nucleic acid; obtain single stranded nucleotide sequences, incubate with denatured nucleotide sequences, amplify determining sequence of nucleotide sequence TRUSTEES OF BOSTON UNIVERSITY, THE 2003-05-22 US disclosed
EP-1262564-A2 Dna sequencing by mass spectrometry SEQUENOM, INC. (US) 2002-12-04 EP disclosed
US-6436635-B1 HYBRIDIZATION AND COMPLEXING WITH SINGLE-STRANDED NUCLEIC ACIDS; LIGATION TO PROBE; DISPLACEMENT POLYMERIZATION OF UNLIGATED STRAND; GENETIC ENGINEERING BOSTON UNIVERSITY 2002-08-20 US disclosed
US-6238871-B1 HIGH SPEED; HIGH THROUGHPUT; NO REQUIRED ELECTROPHORESIS; SANGER SEQUENCING STRATEGY, THEN DETERMINING SEQUENCE BY ALIGNING TERMINATED FRAGMENTS ACCORDING TO MOLECULAR WEIGHT SEQUENOM, INC. 2001-05-29 US disclosed
EP-0679196-A1 DNA SEQUENCING BY MASS SPECTROMETRY SEQUENOM, INC. (US) 1995-11-02 EP disclosed
WO-1994016101-A2 DNA SEQUENCING BY MASS SPECTROMETRY KOESTER HUBERT (US) 1994-07-21 WO disclosed
EP-0270651-B1 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES CALIFORNIA INST OF TECHN (US) 1994-06-15 EP disclosed
US-5118800-A Oligonucleotides possessing a primary amino group in the terminal nucleotide CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-06-02 US disclosed
US-5118802-A DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-06-02 US disclosed
US-5015733-A Phosphoramidites and oligonucleotides derived therefrom CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1991-05-14 US disclosed
US-4849513-A Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1989-07-18 US disclosed
EP-0270651-A4 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. CALIFORNIA INST OF TECHN (US) 1989-03-29 EP disclosed
EP-0270651-A1 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. CALIFORNIA INST OF TECHN (US) 1988-06-15 EP disclosed
WO-1988000201-A1 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES CALIFORNIA INSTITUTE OF TECHNOLOGY, INC. (US) 1988-01-14 WO disclosed