Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KAT7 | O95251 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354266 | 0.79 | HTT (0.56) | HTTHDAC1HDAC6MEN1TSHR | |
| SCHEMBL31691458 | 0.78 | HTT (0.55) | HTTHDAC1HDAC6KDM5AKDM4C | |
| SCHEMBL31691247 | 0.76 | HTT (0.60) | HTTHDAC1HDAC6KDM5AKDM4C | |
| SCHEMBL31691283 | 0.76 | HTT (0.60) | HTTHDAC1HDAC6KDM5AKDM4C | |
| SCHEMBL31691462 | 0.76 | HTT (0.60) | HTTHDAC1HDAC6KDM5AKDM4C | |
| SCHEMBL31691366 | 0.76 | HTT (0.60) | HTTHDAC1HDAC6KDM5AKDM4C | |
| SCHEMBL31691461 | 0.76 | HTT (0.56) | HTTHDAC1HDAC6KDM5AKDM4C | |
| SCHEMBL31172762 | 0.76 | HTT (0.56) | HTTHDAC1HDAC6MEN1TSHR | |
| SCHEMBL31172671 | 0.76 | HTT (0.56) | HTTHDAC1HDAC6MEN1TSHR | |
| SCHEMBL31691315 | 0.75 | HTT (0.55) | HTTHDAC1HDAC6KDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020156106-A1 | HETEROCYCLIC ARYL FORMAMIDES OR SALT THEREOF, PREPARATION METHOD, WEEDING COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2020-08-06 | — | — | WO | disclosed |