Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26328495 | 0.82 | CYP2D6 (0.36) | CYP2D6HRH3KDM4EMEN1ALDH1A1 | |
| SCHEMBL25089980 | 0.81 | CYP2D6 (0.33) | CYP2D6HRH3 | |
| SCHEMBL24941848 | 0.80 | CYP2D6 (0.35) | CYP2D6HRH3 | |
| SCHEMBL24865919 | 0.78 | CYP2D6 (0.34) | CYP2D6HRH3 | |
| SCHEMBL24941937 | 0.77 | CYP2D6 (0.33) | CYP2D6HRH3 | |
| SCHEMBL21142413 | 0.77 | CYP2D6 (0.33) | CYP2D6HRH3 | |
| SCHEMBL19122147 | 0.73 | HRH3 (0.35) | CYP2D6HRH3 | |
| SCHEMBL24754046 | 0.73 | HRH3 (0.35) | CYP2D6HRH3 | |
| SCHEMBL8064563 | 0.72 | CYP2D6 (0.41) | CYP2D6HRH3KDM4EMEN1ALDH1A1 | |
| SCHEMBL15960697 | 0.70 | CYP2D6 (0.39) | CYP2D6HRH3KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160198-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |