Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | HTT | P42858 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RAD52 | P43351 | 2/20 | 0.54 |
| ▸ | RGS12 | O14924 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL22320982 | 1.00 | KDM4E (0.54) | KDM4ESMN1; SMN2MEN1KMT2ANPC1 | |
| Iodide SCHEMBL9038443 | 1.00 | KDM4E (0.54) | KDM4ESMN1; SMN2MEN1KMT2ANPC1 | |
| Iodide SCHEMBL22320981 | 1.00 | KDM4E (0.54) | KDM4ESMN1; SMN2MEN1KMT2ANPC1 | |
| Iodide SCHEMBL8930202 | 1.00 | KDM4E (0.54) | KDM4ESMN1; SMN2MEN1KMT2ANPC1 | |
| Iodide SCHEMBL22320974 | 1.00 | KDM4E (0.54) | KDM4ESMN1; SMN2MEN1KMT2ANPC1 | |
| Iodide SCHEMBL22320985 | 1.00 | KDM4E (0.54) | KDM4ESMN1; SMN2MEN1KMT2ANPC1 | |
| Iodide SCHEMBL22320952 | 1.00 | KDM4E (0.54) | KDM4ESMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9722985 | 0.98 | KDM4E (0.51) | KDM4ESMN1; SMN2MEN1KMT2ANPC1 | |
| Iodide SCHEMBL22320990 | 0.98 | KDM4E (0.51) | KDM4ESMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9155741 | 0.98 | KDM4E (0.51) | KDM4ESMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11359975-B2 | Using ionic liquids in a programmable sensor | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2022-06-14 | — | — | US | claimed |
| US-20200256744-A1 | USING IONIC LIQUIDS IN A PROGRAMMABLE SENSOR | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2020-08-13 | — | — | US | claimed |
| US-11359975-B2 | Using ionic liquids in a programmable sensor | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2022-06-14 | — | — | US | disclosed |
| US-20200256744-A1 | USING IONIC LIQUIDS IN A PROGRAMMABLE SENSOR | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2020-08-13 | — | — | US | disclosed |