SCHEMBL22320996

SCHEMBL22320996

COc1cc(-c2cc(C)ccc2-c2cc(C(C)(C)C)cc(C34CC5CC(CC(C5)C3)C4)c2O)nc(-c2cc(C)ccc2-c2cc(C(C)(C)C)cc(C34CC5CC(CC(C5)C3)C4)c2O)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.36
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
RARA P10276 2/20 0.34
RARB P10826 2/20 0.34
RARG P13631 2/20 0.34
NR1I2 O75469 1/20 0.34
LMNA P02545 1/20 0.34
PGR P06401 1/20 0.34
HSPD1 P10809 1/20 0.34
GOT1 P17174 1/20 0.34
GLRA1 P23415 1/20 0.34
BLM P54132 1/20 0.34
HSPE1 P61604 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PPARG P37231 1/20 0.32
IKBKB O14920 1/20 0.32
TP53 P04637 2/20 0.30
MAPT P10636 2/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435382 1.00 CNR2 (0.36) CNR2KMT2AMEN1RARARARB
SCHEMBL29435392 0.92 KMT2A (0.34) CNR2KMT2AMEN1RARARARB
SCHEMBL22321076 0.92 KMT2A (0.34) CNR2KMT2AMEN1RARARARB
SCHEMBL22321087 0.89 KMT2A (0.35) CNR2KMT2AMEN1RARARARB
SCHEMBL29435380 0.89 KMT2A (0.35) CNR2KMT2AMEN1RARARARB
SCHEMBL22321049 0.88 CNR2 (0.38) CNR2IKBKBKDM4E
SCHEMBL29435388 0.88 CNR2 (0.38) CNR2IKBKBKDM4E
SCHEMBL29435386 0.88 CNR2 (0.38) CNR2IKBKBKDM4E
SCHEMBL22321073 0.88 CNR2 (0.33) CNR2KMT2AMEN1RARARARB
SCHEMBL29435403 0.88 CNR2 (0.33) CNR2KMT2AMEN1RARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11254763-B2 Transition metal bis(phenolate) complexes and their use as catalysts for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-02-22 US disclosed
US-11254763-B2 Transition metal bis(phenolate) complexes and their use as catalysts for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-02-22 US disclosed
WO-2020167821-A1 TRANSITION METAL BIS(PHENOLATE) COMPLEXES AND THEIR USE AS CATALYSTS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-08-20 WO disclosed
US-20200255553-A1 Transition Metal Bis(Phenolate) Complexes and Their Use as Catalysts for Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2020-08-13 US disclosed
US-20200255553-A1 Transition Metal Bis(Phenolate) Complexes and Their Use as Catalysts for Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2020-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11254763-B2 Transition metal bis(phenolate) complexes and their use as catalysts for olefin polymerization CCNT1, CCNA1, CCNE2 CNR2 2041/4885KMT2A 772/4885MEN1 2396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.