Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27579467 | 0.79 | KLK7 (0.46) | KLK7STSGPR119JAK2JAK1 | |
| SCHEMBL22324617 | 0.78 | ABCB1 (0.42) | KLK7STSGPR119JAK2JAK1 | |
| SCHEMBL21996514 | 0.78 | ABCB1 (0.42) | KLK7STSGPR119JAK2JAK1 | |
| SCHEMBL3249107 | 0.76 | STS (0.58) | STSGPR119JAK2JAK1LMNA | |
| SCHEMBL21996403 | 0.76 | KDM1A (0.39) | GPR119KDM4EKDM1ASMN1; SMN2THRB | |
| SCHEMBL15720471 | 0.76 | STS (0.47) | KLK7STSDDB1CRBNGPR119 | |
| SCHEMBL24535177 | 0.74 | STS (0.48) | KLK7STSDDB1CRBNGPR119 | |
| SCHEMBL22355152 | 0.74 | TMEM97 (0.43) | KLK7STSGPR119LMNAKDM4E | |
| SCHEMBL942191 | 0.74 | JAK2 (0.55) | KLK7STSGPR119JAK2JAK1 | |
| SCHEMBL20503925 | 0.74 | JAK2 (0.55) | KLK7STSGPR119JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232350-A | A method of preparing N-Boc-3- pyrrolidine formaldehyde | 辽宁东科药业有限公司 | 2019-01-18 | — | — | CN | claimed |
| WO-2020113077-A9 | COMPOSITIONS AND METHODS FOR MODULAR CONTROL OF BIOORTHOGONAL LIGATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-08-13 | — | — | WO | disclosed |
| CN-109232350-A | A method of preparing N-Boc-3- pyrrolidine formaldehyde | 辽宁东科药业有限公司 | 2019-01-18 | — | — | CN | disclosed |
| CN-109232350-A | A method of preparing N-Boc-3- pyrrolidine formaldehyde | 辽宁东科药业有限公司 | 2019-01-18 | — | — | CN | disclosed |