SCHEMBL22324

SCHEMBL22324

O=C(O)C1(Cl)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11173116 0.97
SCHEMBL1033587 0.87
SCHEMBL243671 0.87
SCHEMBL16198150 0.86 FFAR3 (0.32)
Bromide SCHEMBL11813561 0.84
SCHEMBL1421 0.84 CYP2C19 (0.42)
SCHEMBL1477910 0.84 CYP2C19 (0.42)
Hydrochloric Acid SCHEMBL11815237 0.84
SCHEMBL6917012 0.82 CYP2C19 (0.41)
Hydrochloric Acid SCHEMBL11815475 0.82 CYP2C19 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 806 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3241829-B1 HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2020-12-23 EP claimed
EP-2921485-B1 ISOXAZOLE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2018-07-18 EP claimed
EP-2921484-B1 OXAZOLE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2018-07-18 EP claimed
EP-2921495-B1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES BAYER IP GMBH (DE) 2018-03-28 EP claimed
US-9924721-B2 Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-03-27 US claimed
EP-3013821-B1 PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2018-03-14 EP claimed
US-9717243-B2 Piperidinecarboxylic acid derivatives as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-08-01 US claimed
US-20160198713-A1 Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-07-14 US claimed
EP-3039023-A1 MALONIC ESTER DERIVATIVES OF HETEROARYLPIPERIDINES AND -PIPERAZINES AS FUNGICIDES Bayer CropScience Aktiengesellschaft (DE) 2016-07-06 EP claimed
US-20160135461-A1 PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-05-19 US claimed
EP-1989944-B1 Substituted cyclopropane carbolic acid(3-methyl-cyclohexyl)amides as taste substances SYMRISE GMBH & CO KG (DE) 2010-06-02 EP claimed
US-20080292763-A1 Substituted Cyclopropanecarboxylic acid (3-methyl-cyclohexyl)amide as flavoring substance SYMRISE GMBH & CO. KG (DE) 2008-11-27 US claimed
EP-0312124-A2 Process for the preparation of optically-active cyanomethyl esters E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-19 EP claimed
US-4723027-A TREATING AN ALDEHYDE WITH HYDROGEN CYANIDE IN THE PRESENCE OF CYCLO(D-PHENYLALANYL-D-HISTIDINE)CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-02-02 US claimed
EP-0112133-B1 5-PHENYLETHENYLBENZIMIDAZOLES SMITHKLINE BECKMAN CORPORATION (US) 1987-10-21 EP claimed
EP-0112133-A1 5-Phenylethenylbenzimidazoles SMITHKLINE BECKMAN CORPORATION (US) 1984-06-27 EP claimed
EP-0109681-A2 process for the preparation of optically-active cyanomethyl esters E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-30 EP claimed
EP-0007070-B1 2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS HAVING DOPAMINE RECEPTOR BLOCKING ACTIVITY SMITHKLINE BECKMAN CORPORATION (US) 1983-01-19 EP claimed
US-4211727-A CADMIUM BOROHYDRIDE COMPLEX AS REDUCING AGENT SHELL OIL COMPANY (US) 1980-07-08 US claimed
EP-0007070-A1 2,3,4,5-Tetrahydro-1H-3-Benzazepines, process for their production and pharmaceutical compositions having dopamine receptor blocking activity SMITHKLINE BECKMAN CORPORATION (US) 1980-01-23 EP claimed