Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 15/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.52 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22335795 | 0.89 | CYP4F2 (0.55) | MRGPRX4SMN1; SMN2CYP4F2CYP4A11ALKBH1 | |
| SCHEMBL20590806 | 0.84 | NPC1 (0.54) | TP53NFKB1NFKB2RELASMN1; SMN2 | |
| SCHEMBL22325491 | 0.82 | CYP4F2 (0.61) | MRGPRX4SMN1; SMN2RAB9ACYP4F2CYP4A11 | |
| SCHEMBL22968107 | 0.80 | CYP4F2 (0.53) | CYP4F2CYP4A11 | |
| SCHEMBL22335800 | 0.76 | CYP4F2 (0.53) | CYP4F2CYP4A11 | |
| SCHEMBL15167297 | 0.75 | EGLN1 (0.74) | ALKBH1 | |
| SCHEMBL22335796 | 0.74 | MAPT (0.51) | SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL600130 | 0.74 | MAPT (0.64) | SMN1; SMN2 | |
| SCHEMBL18906070 | 0.74 | MRGPRX4 (0.67) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL22480878 | 0.72 | MRGPRX4 (1.00) | MRGPRX4TP53PKMNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162612-A1 | PYRIDINE COMPOUND SUBSTITUTED BY HETEROARYL | 大正製薬株式会社 | 2020-08-13 | — | — | WO | disclosed |