Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.56 |
| ▸ | CA2 | P00918 | 12/20 | 0.56 |
| ▸ | CA12 | O43570 | 7/20 | 0.56 |
| ▸ | CA9 | Q16790 | 7/20 | 0.56 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326309 | 1.00 | CA1 (0.56) | CA1CA2CA12CA9CCNC | |
| SCHEMBL22326318 | 1.00 | CA1 (0.56) | CA1CA2CA12CA9CCNC | |
| SCHEMBL22326324 | 1.00 | CA1 (0.56) | CA1CA2CA12CA9CCNC | |
| SCHEMBL17162051 | 0.93 | CA1 (0.55) | CA1CA2CA12CA9CCNC | |
| SCHEMBL2822013 | 0.93 | CA1 (0.60) | CA1CA2CA12CA9CCNC | |
| SCHEMBL22326317 | 0.92 | CA1 (0.51) | CA1CA2CA12CA9CCNC | |
| SCHEMBL27138446 | 0.92 | CA1 (0.55) | CA1CA2CA12CA9CCNC | |
| SCHEMBL23835564 | 0.92 | CA1 (0.61) | CA1CA2CA12CA9CCNC | |
| SCHEMBL21071071 | 0.92 | CA1 (0.52) | CA1CA2CA12CA9CCNC | |
| SCHEMBL8073830 | 0.92 | CA1 (0.52) | CA1CA2CA12CA9CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162725-A1 | TARGET PROTEIN EED DEGRADATION-INDUCING DEGRADUCER, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATED TO EED, EZH2, OR PRC2, COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2020-08-13 | — | — | WO | disclosed |