Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.40 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326294 | 1.00 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL21068628 | 1.00 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL21070962 | 0.98 | MEN1 (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL22326327 | 0.98 | MEN1 (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL25369822 | 0.98 | MEN1 (0.42) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL21070920 | 0.96 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL21069080 | 0.94 | MEN1 (0.46) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL19306452 | 0.92 | TSHR (0.43) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL25385542 | 0.85 | MEN1 (0.50) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL23636435 | 0.85 | MEN1 (0.50) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162725-A1 | TARGET PROTEIN EED DEGRADATION-INDUCING DEGRADUCER, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATED TO EED, EZH2, OR PRC2, COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2020-08-13 | — | — | WO | disclosed |