Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | FABP1 | P07148 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402581 | 0.86 | PLA2G4B (0.64) | PLA2G4BCNR1CNR2PPARGPPARA | |
| SCHEMBL22326304 | 0.85 | PLA2G4B (0.48) | PLA2G4BCNR1CNR2KDM4EALDH1A1 | |
| SCHEMBL3467446 | 0.84 | PLA2G4B (0.57) | PLA2G4BKDM4EALDH1A1GAAPOLB | |
| SCHEMBL2767522 | 0.83 | SLC7A5 (0.48) | PLA2G4BKDM4EALDH1A1GAAPOLB | |
| SCHEMBL7804122 | 0.83 | PLA2G4B (0.60) | PLA2G4BKDM4EALDH1A1GAAPPARG | |
| SCHEMBL25495951 | 0.83 | CHRM2 (0.49) | PLA2G4BKDM4EALDH1A1GAAPOLB | |
| SCHEMBL4147607 | 0.83 | KDM4E (0.53) | PLA2G4BKDM4EALDH1A1GAAPOLB | |
| SCHEMBL3984588 | 0.82 | SLC7A5 (0.50) | PLA2G4BKDM4EALDH1A1GAAPOLB | |
| SCHEMBL3868045 | 0.82 | SLC7A5 (0.47) | PLA2G4BKDM4EALDH1A1GAAPOLB | |
| SCHEMBL3979830 | 0.82 | SLC7A5 (0.47) | PLA2G4BKDM4EALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162725-A1 | TARGET PROTEIN EED DEGRADATION-INDUCING DEGRADUCER, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATED TO EED, EZH2, OR PRC2, COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2020-08-13 | — | — | WO | disclosed |