Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233169 | 0.80 | KMT2A (0.47) | NR4A2MAOBMAOAALKBH1NPC1 | |
| SCHEMBL2236662 | 0.79 | NR4A2 (0.48) | NR4A2MAOBMAOAALKBH1NPC1 | |
| SCHEMBL2236651 | 0.79 | NR4A2 (0.48) | NR4A2MAOBMAOAALKBH1NPC1 | |
| SCHEMBL2235542 | 0.79 | NR4A2 (0.41) | NR4A2MAOBMAOAALKBH1NPC1 | |
| SCHEMBL2231739 | 0.77 | NR4A2 (0.60) | NR4A2MAOBMAOAALKBH1NPC1 | |
| SCHEMBL13582548 | 0.76 | MAOB (0.45) | NR4A2MAOBMAOAALKBH1NPC1 | |
| SCHEMBL13582546 | 0.76 | MAOB (0.45) | NR4A2MAOBMAOAALKBH1NPC1 | |
| SCHEMBL13582543 | 0.76 | MAOB (0.45) | NR4A2MAOBMAOAALKBH1NPC1 | |
| SCHEMBL2233162 | 0.75 | CA12 (0.46) | NR4A2MAOBMAOANPC1RAB9A | |
| SCHEMBL2231831 | 0.75 | KMT2A (0.41) | NR4A2MAOBMAOAALKBH1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |