Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2236767 | 0.90 | HTR2A (0.45) | BCL9CTNNB1HTR2AGAAMAPT | |
| SCHEMBL2235180 | 0.89 | BCL9 (0.48) | BCL9CTNNB1HTR2AGAAMAPT | |
| SCHEMBL12426959 | 0.87 | BCL9 (0.44) | BCL9CTNNB1HTR2AGAAMAPT | |
| SCHEMBL2236108 | 0.87 | BCL9 (0.46) | BCL9CTNNB1HTR2AGAAMAPT | |
| SCHEMBL2234610 | 0.83 | BCL9 (0.68) | BCL9CTNNB1HTR2AGAAMAPT | |
| SCHEMBL22364373 | 0.81 | HTR2A (0.45) | BCL9CTNNB1HTR2AGAAMAPT | |
| SCHEMBL22364451 | 0.80 | HTR2A (0.46) | BCL9CTNNB1HTR2AGAAMAPT | |
| SCHEMBL2235137 | 0.80 | BCL9 (0.56) | BCL9CTNNB1HTR2AGAAMAPT | |
| SCHEMBL6447049 | 0.80 | BCL9 (0.53) | BCL9CTNNB1HTR2AGAAMAPT | |
| SCHEMBL12348677 | 0.79 | BCL9 (0.43) | BCL9CTNNB1HTR2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101245-A1 | NITRIC OXIDE RELEASING COMPOUNDS FOR THE TREATMENT OF NEUROPATHIC PAIN | NICOX S.A. (FR) | 2011-08-25 | — | — | WO | disclosed |
| WO-2011092065-A1 | NITRIC OXIDE RELEASING COMPOUNDS FOR THE TREATMENT OF NEUROPHATIC PAIN | NICOX S.A. (FR) | 2011-08-04 | — | — | WO | disclosed |