Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10335833 | 0.93 | PDE4D (0.41) | MAPTKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL1243321 | 0.91 | ESR1 (0.48) | LTA4HESR1L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL9419349 | 0.89 | ESR1 (0.48) | MAPTMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL29362239 | 0.89 | ESR1 (0.48) | MAPTMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL19450271 | 0.88 | MAPT (0.48) | MAPTKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL9419297 | 0.87 | ESR1 (0.50) | MAPTMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL9419252 | 0.87 | ESR1 (0.50) | MAPTMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL7557774 | 0.87 | ESR1 (0.50) | MAPTMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL9419240 | 0.87 | ESR1 (0.50) | MAPTMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL10336186 | 0.87 | NR5A1 (0.47) | MAPTMEN1TP53KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087764-A | Deprotonation of a 1-substituted-2,3-difluorobenzene using an organometallic compound and reacting the reaction product with an electrophile | Merck Patent Gesellschaft mit beschrankter Hafung (DE) | 1992-02-11 | — | — | US | claimed |
| CN-110922306-B | Synthesis process of 2, 3-difluoro-4-alkoxyl phenol | 蚌埠中实化学技术有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-115926807-A | Liquid crystal medium and application | 深圳市和力信材料有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-107345140-B | Liquid crystal compound with isobutyl negative dielectric anisotropy and application thereof | 北京八亿时空液晶科技股份有限公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-109575936-B | Liquid crystal compound, liquid crystal composition, and liquid crystal display element | 达兴材料股份有限公司 | 2020-11-03 | — | — | CN | disclosed |
| CN-110922306-A | Synthesis process of 2, 3-difluoro-4-alkoxy phenol | 蚌埠中实化学技术有限公司 | 2020-03-27 | — | — | CN | disclosed |
| CN-109575936-A | Liquid crystal compound, liquid crystal composition, and liquid crystal display element | 达兴材料股份有限公司 | 2019-04-05 | — | — | CN | disclosed |
| US-9777216-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2017-10-03 | — | — | US | disclosed |
| CN-105295947-A | Manufacturing method by contacting hydrogen reduction | DAINIPPON INK & CHEMICALS | 2016-02-03 | — | — | CN | disclosed |
| EP-2534223-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-10-21 | — | — | EP | disclosed |
| EP-2534223-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2012-12-19 | — | — | EP | disclosed |
| US-20120305843-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
| CN-102753653-A | Liquid crystalline medium | MERCK PATENT GMBH | 2012-10-24 | — | — | CN | disclosed |
| WO-2011098224-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2011-08-18 | — | — | WO | disclosed |
| EP-0363458-B1 | 2,3-DIFLUOROBENZENES | MERCK PATENT GMBH (DE) | 1994-08-03 | — | — | EP | disclosed |
| US-5087764-A | Deprotonation of a 1-substituted-2,3-difluorobenzene using an organometallic compound and reacting the reaction product with an electrophile | Merck Patent Gesellschaft mit beschrankter Hafung (DE) | 1992-02-11 | — | — | US | disclosed |
| EP-0363458-A1 | 2,3-DIFLUOROBENZENES. | MERCK PATENT GMBH (DE) | 1990-04-18 | — | — | EP | disclosed |
| WO-1989008629-A1 | PROCESS FOR PREPARING 2,3-DIFLUOROBENZENES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120305843-A1 | LIQUID CRYSTALLINE MEDIUM | NEFM, VIM, PLG | MAPT 267/4885KDM4E 3357/4885MEN1 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.