Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.81 |
| ▸ | RCOR1 | Q9UKL0 | 11/20 | 0.81 |
| ▸ | MAOA | P21397 | 11/20 | 0.81 |
| ▸ | KDM1B | Q8NB78 | 9/20 | 0.81 |
| ▸ | MAOB | P27338 | 8/20 | 0.81 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22335119 | 0.91 | KDM1A (0.82) | KDM1ARCOR1MAOAKDM1BMAOB | |
| SCHEMBL17287400 | 0.90 | KDM1A (1.00) | KDM1ARCOR1MAOAKDM1BMAOB | |
| SCHEMBL17287398 | 0.90 | KDM1A (1.00) | KDM1ARCOR1MAOAKDM1BMAOB | |
| Hydrochloric Acid SCHEMBL17287370 | 0.89 | KDM1A (1.00) | KDM1ARCOR1MAOAKDM1BMAOB | |
| Hydrochloric Acid SCHEMBL17287369 | 0.89 | KDM1A (1.00) | KDM1ARCOR1MAOAKDM1BMAOB | |
| SCHEMBL17302731 | 0.86 | KDM1A (0.76) | KDM1ARCOR1MAOAKDM1BMAOB | |
| SCHEMBL15778035 | 0.84 | KDM1A (0.73) | KDM1ARCOR1MAOAKDM1BMAOB | |
| SCHEMBL15778034 | 0.84 | KDM1A (0.73) | KDM1ARCOR1MAOAKDM1BMAOB | |
| SCHEMBL15787401 | 0.84 | KDM1A (0.73) | KDM1ARCOR1MAOAKDM1BMAOB | |
| SCHEMBL22334935 | 0.82 | KDM1A (0.75) | KDM1ARCOR1MAOAKDM1BMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928457-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS INHIBITORS OF HISTONE DEMETHYLASES KDM1A | ST EUROPEO DI ONCOLOGIA S R L (IT) | 2020-08-12 | — | — | EP | disclosed |