SCHEMBL22337372

SCHEMBL22337372

CC(=O)Nc1ncc(CN2CC(O[Si](C)(C)C(C)(C)C)C[C@@H]2C)s1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 19/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496523 1.00 OGA (0.49) OGA
SCHEMBL31051534 0.82 OGA (0.52) OGA
SCHEMBL22323327 0.82 OGA (0.55) OGA
SCHEMBL22337382 0.82 OGA (0.55) OGA
SCHEMBL21807919 0.82 OGA (0.55) OGA
SCHEMBL31128712 0.81 OGA (0.52) OGA
SCHEMBL31051509 0.81 OGA (0.47) OGA
SCHEMBL31128787 0.81 OGA (0.49) OGA
SCHEMBL31128694 0.81 OGA (0.54) OGA
SCHEMBL31128752 0.81 OGA (0.54) OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020163193-A1 BICYCLIC ETHER O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS BIOGEN MA INC. (US) 2020-08-13 — — WO disclosed
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