Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30486800 | 0.86 | TP53 (0.51) | TP53CHRM3TSHRSMN1; SMN2MEN1 | |
| SCHEMBL22337503 | 0.86 | TP53 (0.51) | TP53CHRM3TSHRSMN1; SMN2MEN1 | |
| SCHEMBL22337322 | 0.86 | TP53 (0.51) | TP53CHRM3TSHRSMN1; SMN2MEN1 | |
| SCHEMBL22591707 | 0.79 | TP53 (0.49) | TP53CHRM3TSHRSMN1; SMN2MEN1 | |
| SCHEMBL30486819 | 0.79 | TP53 (0.49) | TP53CHRM3TSHRSMN1; SMN2MEN1 | |
| SCHEMBL27060609 | 0.77 | TP53 (0.52) | TP53CHRM3TSHRSMN1; SMN2MEN1 | |
| SCHEMBL23386315 | 0.77 | TP53 (0.44) | TP53CHRM3TSHRSMN1; SMN2MEN1 | |
| SCHEMBL23911987 | 0.76 | TP53 (0.48) | TP53CHRM3TSHRSMN1; SMN2MEN1 | |
| SCHEMBL21662059 | 0.75 | KMT2A (0.53) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL30486807 | 0.75 | KMT2A (0.53) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022033893-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |
| WO-2020161148-A2 | PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020161147-A1 | HERBICIDAL MIXTURES | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |