Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.57 |
| ▸ | F2 | P00734 | 5/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233758 | 1.00 | F10 (0.57) | F10F2ABCB11ST14PTGS2 | |
| SCHEMBL16706296 | 0.86 | F10 (0.66) | F10F2ABCB11ST14PTGS2 | |
| SCHEMBL18843493 | 0.81 | F10 (0.58) | F10F2ABCB11ST14PTGS2 | |
| SCHEMBL5625141 | 0.77 | F10 (0.73) | F10F2ABCB11ST14 | |
| SCHEMBL5628214 | 0.77 | F10 (0.73) | F10F2ABCB11ST14 | |
| SCHEMBL5627627 | 0.77 | F10 (0.73) | F10F2ABCB11ST14 | |
| SCHEMBL5625381 | 0.77 | F10 (0.73) | F10F2ABCB11ST14 | |
| SCHEMBL5625917 | 0.77 | F10 (0.71) | F10F2ABCB11ST14 | |
| SCHEMBL5630405 | 0.77 | F10 (0.71) | F10F2ABCB11ST14 | |
| SCHEMBL16706293 | 0.76 | F10 (0.61) | F10F2ABCB11ST14PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011098501-A1 | METHOD FOR THE PREPARATION OF RIVAROXABAN | SANDOZ AG (CH) | 2011-08-18 | — | — | WO | disclosed |
| EP-2354128-A1 | Method for the preparation of rivaroxaban | SANDOZ AG (CH) | 2011-08-10 | — | — | EP | disclosed |