Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.80 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.80 |
| ▸ | GAK | O14976 | 3/20 | 0.80 |
| ▸ | ILK | Q13418 | 3/20 | 0.80 |
| ▸ | PLK4 | O00444 | 1/20 | 0.80 |
| ▸ | CIT | O14578 | 1/20 | 0.80 |
| ▸ | AURKA | O14965 | 1/20 | 0.80 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.80 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.80 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.80 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.80 |
| ▸ | BUB1 | O43683 | 1/20 | 0.80 |
| ▸ | KDM1A | O60341 | 1/20 | 0.80 |
| ▸ | JAK2 | O60674 | 1/20 | 0.80 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.80 |
| ▸ | STK17B | O94768 | 1/20 | 0.80 |
| ▸ | STK10 | O94804 | 1/20 | 0.80 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.80 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.80 |
| ▸ | ABL1 | P00519 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1507528 | 1.00 | EGFR (0.80) | EGFRERBB2GAKILKPLK4 | |
| Hydrochloric Acid SCHEMBL1507710 | 0.99 | EGFR (0.80) | EGFRERBB2GAKILKPLK4 | |
| SCHEMBL22336842 | 0.92 | EGFR (0.77) | EGFRERBB2GAKILKPLK4 | |
| SCHEMBL4124144 | 0.92 | EGFR (0.82) | EGFRERBB2GAKILKPLK4 | |
| Hydrochloric Acid SCHEMBL1507607 | 0.91 | EGFR (0.81) | EGFRERBB2GAKILKPLK4 | |
| Erlotinib SCHEMBL30362833 | 0.89 | EGFR (1.00) | EGFRERBB2GAKILKPLK4 | |
| Erlotinib SCHEMBL8413 | 0.89 | EGFR (1.00) | EGFRERBB2GAKILKPLK4 | |
| Erlotinib SCHEMBL3667407 | 0.89 | EGFR (1.00) | EGFRERBB2GAKILKPLK4 | |
| Erlotinib SCHEMBL29351329 | 0.89 | EGFR (1.00) | EGFRERBB2GAKILKPLK4 | |
| Erlotinib SCHEMBL21176918 | 0.88 | EGFR (1.00) | EGFRERBB2GAKILKPLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163594-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |