Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 1.00 |
| ▸ | BCHE | P06276 | 1/20 | 0.74 |
| ▸ | ACHE | P22303 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | DRD2 | P14416 | 2/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | DRD4 | P21917 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dauricine SCHEMBL22089144 | 1.00 | KCNH2 (1.00) | KCNH2BCHEACHEKDM4EALDH1A1 | |
| Dauricine SCHEMBL29494083 | 1.00 | KCNH2 (1.00) | KCNH2BCHEACHEKDM4EALDH1A1 | |
| Dauricine SCHEMBL28689430 | 1.00 | KCNH2 (1.00) | KCNH2BCHEACHEKDM4EALDH1A1 | |
| Dauricine SCHEMBL677474 | 1.00 | KCNH2 (1.00) | KCNH2BCHEACHEKDM4EALDH1A1 | |
| Dauricine SCHEMBL29494084 | 1.00 | KCNH2 (1.00) | KCNH2BCHEACHEKDM4EALDH1A1 | |
| Daruisoline SCHEMBL24212114 | 0.97 | KCNH2 (1.00) | KCNH2BCHEACHEKDM4EALDH1A1 | |
| Daruisoline SCHEMBL31192245 | 0.97 | KCNH2 (1.00) | KCNH2BCHEACHEKDM4EALDH1A1 | |
| SCHEMBL29411700 | 0.97 | KCNH2 (0.96) | KCNH2BCHEACHEKDM4EALDH1A1 | |
| SCHEMBL21125616 | 0.95 | KCNH2 (0.90) | KCNH2BCHEACHEKDM4EALDH1A1 | |
| SCHEMBL28672292 | 0.95 | KCNH2 (0.90) | KCNH2BCHEACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 614 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120121754-A | Construction method of HPLC (high Performance liquid chromatography) characteristic spectrum of rhizoma Menispermi medicinal decoction pieces, standard decoction and formula granules | 四川新绿色药业科技发展有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-116262117-B | Application of isoquinoline alkaloid in treating echinococcosis | 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心) | 2025-05-06 | — | — | CN | claimed |
| CN-117510408-B | Antiviral traditional Chinese medicine monomer dauricine, pharmaceutical composition and application thereof | 北京中医药大学 | 2025-03-28 | — | — | CN | claimed |
| CN-119632985-A | Application of dauricine in preparation of medicine for treating non-small cell lung cancer | 沃纳生物智能科技(广东省横琴)有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119595779-A | Construction method and identification method of rhizoma Menispermi medicinal material and formula granule UPLC (unified power control) map | 劲牌持正堂药业有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119454708-A | Application of dauricine in preparation of medicine for treating diabetes | 中南民族大学 | 2025-02-18 | — | — | CN | claimed |
| CN-118743700-A | Application of dauricine in preparation of antidepressant | 辽宁大学 | 2024-10-08 | — | — | CN | claimed |
| US-20240206523-A1 | Compound of reaction of alkaloid and phenol, atomization liquid, cartomizer and electronic atomizer | ZHANG, QI (CN) | 2024-06-27 | — | — | US | claimed |
| WO-2024104415-A1 | BISBENZYLISOQUINOLINE COMPOUNDS AS FERROPTOSIS INHIBITORS | Hangzhou Jianlai Biotechnology Co., Ltd. (CN) | 2024-05-23 | — | — | WO | claimed |
| WO-2024088403-A1 | USE OF ISOQUINOLINE ALKALOID IN PREVENTION AND TREATMENT OF DISEASES CAUSED BY CORONAVIRAL INFECTIONS | 北京化工大学 | 2024-05-02 | — | — | WO | claimed |
| CN-101704783-A | Preparation method of dauricine | NANJING RUNS PHARMACEUTICAL TE | 2010-05-12 | — | — | CN | claimed |
| CN-1939417-A | Medicinal composition of douricine, tinosporae or its extract | CAI JUN (CN) | 2007-04-04 | — | — | CN | claimed |
| CN-1939413-A | Compound douricien medicinal composition and its preparation | CAI JUN (CN) | 2007-04-04 | — | — | CN | claimed |
| CN-1939412-A | Medicinal composition with dauricine and houttuynin sodium | CAI JUN (CN) | 2007-04-04 | — | — | CN | claimed |
| CN-1569777-A | Chiral source and pharmaceutical salt or complex of organic alkali drug | GAO BINGYUAN (CN) | 2005-01-26 | — | — | CN | claimed |
| EP-0889731-B1 | INJECTABLE THERAPY FOR CONTROL OF MUSCLE SPASMS AND PAIN RELATED TO MUSCLE SPASMS | ALLERGAN INC (US) | 2004-11-24 | — | — | EP | claimed |
| CN-1424112-A | Water soluble dressing for insoluble medicines and preparation thereof | SHANGHAI MEDICAL POLYTECHNIC A (CN) | 2003-06-18 | — | — | CN | claimed |
| CN-1041992-C | Preparation technology of cold resistant panacla tablet | SHENYANG TRADITIONAL CHINESE M (CN) | 1999-02-10 | — | — | CN | claimed |
| CN-1062088-A | PREPARATION TECHNOLOGY OF COLD RESISTANT PANACLA TABLET | SHENYANG TRADITIONAL CHINESE M (CN) | 1992-06-24 | — | — | CN | claimed |
| CN-1047861-A | From yellow parilla, extract the technology of dauricine | TONGJI MEDICAL UNIV (CN) | 1990-12-19 | — | — | CN | claimed |