SCHEMBL22341870

SCHEMBL22341870

C#COc1cc2cc(-c3cc(CO)cc4nc(OC)cnc34)oc2cc1F

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 17/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30187773 0.91 F2RL3 (0.49) F2RL3
SCHEMBL19783370 0.91 F2RL3 (0.49) F2RL3
SCHEMBL22341939 0.87 F2RL3 (0.46) F2RL3
SCHEMBL22341941 0.87 F2RL3 (0.52) F2RL3
SCHEMBL23463111 0.82 F2RL3 (0.44) F2RL3
SCHEMBL19782575 0.77 F2RL3 (0.52) F2RL3
SCHEMBL30189587 0.77 F2RL3 (0.52) F2RL3
SCHEMBL30187671 0.77 F2RL3 (0.57) F2RL3
SCHEMBL19783458 0.77 F2RL3 (0.57) F2RL3
SCHEMBL21379503 0.77 F2RL3 (0.40) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3484878-B1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL MYERS SQUIBB CO (US) 2020-08-19 EP claimed