Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 11/20 | 0.47 |
| ▸ | ROS1 | P08922 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783549 | 0.79 | F2RL3 (0.66) | F2RL3 | |
| SCHEMBL19782608 | 0.77 | F2RL3 (0.33) | F2RL3 | |
| SCHEMBL20435308 | 0.76 | F2RL3 (0.79) | F2RL3 | |
| SCHEMBL19782609 | 0.74 | F2RL3 (0.32) | F2RL3 | |
| SCHEMBL30189890 | 0.71 | F2RL3 (0.33) | F2RL3 | |
| SCHEMBL21379630 | 0.70 | F2RL3 (0.56) | F2RL3 | |
| SCHEMBL18425079 | 0.69 | F2RL3 (0.74) | F2RL3 | |
| SCHEMBL20435306 | 0.66 | F2RL3 (0.65) | F2RL3TP53NFKB1NFKB2RELA | |
| SCHEMBL9086704 | 0.66 | ADORA2A (0.43) | F2RL3ALDH1A1HPGD | |
| SCHEMBL22341987 | 0.65 | F2RL3 (0.46) | F2RL3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484878-B1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-08-19 | — | — | EP | disclosed |