Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 14/20 | 0.62 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30187624 | 0.88 | F2RL3 (0.69) | F2RL3 | |
| SCHEMBL19782963 | 0.88 | F2RL3 (0.69) | F2RL3 | |
| SCHEMBL21379330 | 0.84 | F2RL3 (0.71) | F2RL3 | |
| SCHEMBL22342075 | 0.84 | F2RL3 (0.57) | F2RL3 | |
| SCHEMBL21395599 | 0.83 | F2RL3 (0.68) | F2RL3 | |
| SCHEMBL30187729 | 0.83 | F2RL3 (0.68) | F2RL3 | |
| SCHEMBL19782635 | 0.81 | F2RL3 (0.64) | F2RL3 | |
| SCHEMBL19783264 | 0.81 | F2RL3 (0.62) | F2RL3 | |
| SCHEMBL30187586 | 0.81 | F2RL3 (0.62) | F2RL3 | |
| SCHEMBL19783780 | 0.80 | F2RL3 (0.57) | F2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484878-B1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-08-19 | — | — | EP | disclosed |