⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409261 | 0.89 | — | — | |
| SCHEMBL2804082 | 0.85 | — | — | |
| SCHEMBL10962824 | 0.78 | — | — | |
| SCHEMBL521972 | 0.78 | — | — | |
| SCHEMBL6525804 | 0.75 | — | — | |
| SCHEMBL6524474 | 0.75 | — | — | |
| SCHEMBL11496639 | 0.74 | — | — | |
| SCHEMBL8031194 | 0.72 | — | — | |
| SCHEMBL11487005 | 0.72 | — | — | |
| SCHEMBL11153546 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2528894-A1 | PROCESSES FOR THE PREPARATION OF (R)-2-(7-(4-CYCLOPENTYL-3-(TRIFLUOROMETHYL)BENZYLOXY)-1,2,3,4-TETRAHYDROCYCLOPENTA[B]INDOL-3-YL)ACETIC ACID AND SALTS THEREOF | Arena Pharmaceuticals, Inc. (US) | 2012-12-05 | — | — | EP | disclosed |
| WO-2011094008-A1 | PROCESSES FOR THE PREPARATION OF (R)-2-(7-(4-CYCLOPENTYL-3-(TRIFLUOROMETHYL)BENZYLOXY)-1,2,3,4-TETRAHYDROCYCLOPENTA[B]INDOL-3-YL)ACETIC ACID AND SALTS THEREOF | ARENA PHARMACEUTICALS, INC. (US) | 2011-08-04 | — | — | WO | disclosed |
| US-4232009-A | PROSTAGLANDINS, CYCLODEXTRIN CLATHRATES, HYPOTENSIVES | ONO PHARMACEUTICAL CO. LTD. (JP) | 1980-11-04 | — | — | US | disclosed |