Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22342920 | 0.87 | TYK2 (0.49) | TYK2STAT3 | |
| SCHEMBL22342916 | 0.86 | TYK2 (0.58) | TYK2 | |
| SCHEMBL22343317 | 0.84 | TYK2 (0.69) | TYK2 | |
| SCHEMBL22342919 | 0.78 | TYK2 (0.51) | TYK2 | |
| SCHEMBL22343427 | 0.76 | TYK2 (0.52) | TYK2JAK1PDE4D | |
| SCHEMBL23327741 | 0.75 | TYK2 (0.55) | TYK2 | |
| SCHEMBL23351224 | 0.74 | TYK2 (0.53) | TYK2STAT3PDE4D | |
| SCHEMBL22324243 | 0.73 | TYK2 (0.67) | TYK2JAK1PDE4D | |
| SCHEMBL22342876 | 0.72 | TYK2 (0.63) | TYK2 | |
| SCHEMBL29746672 | 0.72 | TYK2 (0.63) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163778-A1 | TYK2 PSEUDOKINASE LIGANDS | VENTYX BIOSCIENCES, INC. (US) | 2020-08-13 | — | — | WO | disclosed |