Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 19/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22342885 | 0.75 | TYK2 (0.71) | TYK2PDE4D | |
| SCHEMBL22343427 | 0.75 | TYK2 (0.52) | TYK2PDE4D | |
| SCHEMBL22324243 | 0.72 | TYK2 (0.67) | TYK2PDE4D | |
| SCHEMBL23327511 | 0.72 | TYK2 (0.51) | TYK2 | |
| SCHEMBL14158142 | 0.70 | CSNK2B (0.57) | CSNK2BTYK2PDE4D | |
| SCHEMBL2032405 | 0.68 | CSNK2B (0.68) | CSNK2BTYK2PDE4D | |
| SCHEMBL1487862 | 0.67 | CSNK2B (0.62) | CSNK2BTYK2 | |
| SCHEMBL14158073 | 0.67 | CSNK2B (0.40) | CSNK2BTYK2 | |
| SCHEMBL12841015 | 0.66 | CSNK2B (0.61) | CSNK2BTYK2 | |
| SCHEMBL12583268 | 0.66 | CSNK2B (0.61) | CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163778-A1 | TYK2 PSEUDOKINASE LIGANDS | VENTYX BIOSCIENCES, INC. (US) | 2020-08-13 | — | — | WO | disclosed |