Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.58 |
| ▸ | BRD2 | P25440 | 12/20 | 0.58 |
| ▸ | BRD3 | Q15059 | 12/20 | 0.58 |
| ▸ | CCL2 | P13500 | 3/20 | 0.58 |
| ▸ | EP300 | Q09472 | 2/20 | 0.58 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.58 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TAF1 | P21675 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.44 |
| ▸ | BRWD1 | Q9NSI6 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224475 | 0.88 | BRD4 (0.55) | BRD4BRD2BRD3CCL2EP300 | |
| SCHEMBL15993575 | 0.87 | BRD4 (0.52) | BRD4BRD2BRD3 | |
| SCHEMBL223837 | 0.82 | BRD4 (0.68) | BRD4BRD2BRD3CCL2EP300 | |
| SCHEMBL221995 | 0.82 | BRD4 (0.68) | BRD4BRD2BRD3CCL2EP300 | |
| SCHEMBL221673 | 0.79 | BRD4 (0.67) | BRD4BRD2BRD3CCL2EP300 | |
| SCHEMBL220747 | 0.79 | BRD4 (0.67) | BRD4BRD2BRD3CCL2EP300 | |
| SCHEMBL221674 | 0.79 | BRD4 (0.67) | BRD4BRD2BRD3CCL2EP300 | |
| SCHEMBL222925 | 0.76 | BRD4 (0.43) | BRD4BRD2BRD3CCL2EP300 | |
| SCHEMBL5836811 | 0.76 | BRD4 (0.71) | BRD4BRD2BRD3EP300BRDT | |
| SCHEMBL5836805 | 0.76 | BRD4 (0.71) | BRD4BRD2BRD3EP300BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791090-B2 | Prophylactic and/or therapeutic agent for anemia comprising tetrahydroquinoline compound as active ingredient | KOWA COMPANY, LTD. (JP) | 2014-07-29 | — | — | US | disclosed |
| US-20120004197-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT | KOWA COMPANY, LTD. (JP) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004197-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT | EPOR, HBG1, HBG2 | BRD4 861/4885BRD2 1499/4885BRD3 1556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.