Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22345567 | 0.93 | USP7 (0.72) | USP7 | |
| SCHEMBL17868550 | 0.87 | USP7 (0.83) | USP7 | |
| SCHEMBL22345596 | 0.87 | USP7 (0.75) | USP7 | |
| SCHEMBL17893855 | 0.87 | USP7 (0.74) | USP7 | |
| SCHEMBL22345489 | 0.86 | USP7 (0.73) | USP7 | |
| SCHEMBL17868430 | 0.84 | USP7 (0.85) | USP7 | |
| SCHEMBL17868455 | 0.84 | USP7 (1.00) | USP7 | |
| SCHEMBL17868518 | 0.84 | USP7 (1.00) | USP7 | |
| SCHEMBL17868526 | 0.84 | USP7 (0.85) | USP7 | |
| SCHEMBL22345570 | 0.84 | USP7 (0.72) | USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3923987-A1 | USE OF USP7 INHIBITORS FOR THE TREATMENT OF ACUTE MYELOID LEUKEMIA (AML) | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020165315-A1 | USE OF USP7 INHIBITORS FOR THE TREATMENT OF ACUTE MYELOID LEUKEMIA (AML) | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2020-08-20 | — | — | WO | disclosed |