Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.58 |
| ▸ | IL6 | P05231 | 10/20 | 0.58 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29475668 | 0.92 | TLR7 (0.57) | TLR7IL6TLR8 | |
| SCHEMBL26347721 | 0.91 | TLR7 (0.64) | TLR7IL6TLR8 | |
| SCHEMBL26359820 | 0.90 | TLR7 (0.55) | TLR7IL6TLR8 | |
| SCHEMBL26347767 | 0.89 | TLR7 (0.56) | TLR7IL6TLR8 | |
| SCHEMBL28656515 | 0.89 | TLR7 (0.56) | TLR7IL6TLR8 | |
| SCHEMBL26347756 | 0.89 | TLR7 (0.60) | TLR7IL6TLR8 | |
| SCHEMBL26347251 | 0.88 | TLR7 (0.59) | TLR7IL6TLR8 | |
| SCHEMBL26348096 | 0.88 | TLR7 (0.59) | TLR7IL6TLR8 | |
| SCHEMBL26347740 | 0.88 | TLR7 (0.62) | TLR7IL6TLR8 | |
| SCHEMBL22359263 | 0.88 | TLR7 (0.65) | TLR7IL6TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3923991-A1 | COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES | Ambrx, Inc. (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020168017-A1 | COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES | AMBRX, INC. (US) | 2020-08-20 | — | — | WO | disclosed |