Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29458307 | 0.89 | NR1H4 (0.68) | NR1H4 | |
| SCHEMBL29458260 | 0.88 | NR1H4 (0.78) | NR1H4 | |
| SCHEMBL22347962 | 0.87 | NR1H4 (0.79) | NR1H4 | |
| SCHEMBL22348543 | 0.86 | NR1H4 (0.71) | NR1H4 | |
| SCHEMBL31608449 | 0.86 | NR1H4 (0.71) | NR1H4 | |
| SCHEMBL25992661 | 0.85 | NR1H4 (0.87) | NR1H4 | |
| SCHEMBL22348136 | 0.85 | NR1H4 (0.73) | NR1H4 | |
| SCHEMBL31608470 | 0.84 | NR1H4 (0.69) | NR1H4 | |
| SCHEMBL31608427 | 0.84 | NR1H4 (0.81) | NR1H4 | |
| SCHEMBL22348536 | 0.84 | NR1H4 (0.69) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924333-A1 | SUBSTITUTED AMIDE COMPOUNDS USEFUL AS FARNESOID X RECEPTOR MODULATORS | Bristol-Myers Squibb Company (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020168149-A1 | SUBSTITUTED AMIDE COMPOUNDS USEFUL AS FARNESOID X RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-08-20 | — | — | WO | disclosed |